ISSN 1662-4009 (online)

ey0016.2-9 | Gestational Diabetes Mellitus: Neonatal and Long-term Consequences | ESPEYB16

2.9. Diabetes and obesity during pregnancy are associated with oxidative stress genotoxicity in newborns

MF Castilla-Peon , Bravo PG Medina , R Sanchez-Urbina , JM Gallardo-Montoya , LC Soriano-Lopez , Cruz FM Coronel

J Perinat Med. 2019 Apr 24;47(3):347-353. doi: 10.1515/jpm-2018-0201.This study measured 8-hydroxy-deoxyguanosine (8-OH-dG), a marker of DNA oxidative damage, in venous umbilical cord plasma from newborns of mothers with and without a diabetes diagnosis during pregnancy.Adult offspring born to mothers with gestational diabetes mellitus (GDM) have an increased frequency...